Molecular Mechanisms of IL-2 Gene Regulation Following Costimulation Through LFA-1

LFA - 1 Regulation Following Costimulation Through Molecular Mechanisms of IL - 2 Gene

Molecular mechanisms of IL-2 gene regulation following costimulation through LFA-1.

The integrin LFA-1 serves as an accessory molecule in T cell activation. In addition to its well-known role as an adhesion molecule, LFA-1 can contribute to T cell activation and up-regulation of IL-2 gene expression. However, the specific mechanisms by which LFA-1 influences T cell activation have not been elucidated. Therefore, we examined the impact of LFA-1:ICAM-1 interactions on transcript...

Regulation Following Costimulation Through Molecular Mechanisms of IL-2 Gene

of May 21 , 2017 . This information is current as LFA - 1 Regulation Following Costimulation Through Molecular Mechanisms of IL - 2

Proliferation Requires T + LFA - 1 - Mediated Costimulation of CD 8